St John's wort was not better than placebo for reducing symptoms in major depressive disorder.
نویسنده
چکیده
Patients 340 outpatients who were ≥ 18 years of age (mean age 42 y, 66% women); had a current diagnosis of MDD; and scored ≥ 20 on the Hamilton Depression Rating Scale (HDRS) (mean score 22.8) and ≤ 60 on the Global Assessment of Functioning (mean score 53.6) after a 1 week placebo run in period. Exclusion criteria included a score > 2 on the HDRS suicide item, serious physical or psychiatric disorders, use of psychoactive drugs, and pregnancy. Follow up was 99%.
منابع مشابه
Study shows St. John's wort ineffective for major depression.
An extract of the herb St. John’s wort was no more effective for treating major depression of moderate severity than placebo, according to research published in the April 10 issue of the Journal of the American Medical Association. The randomized, double-blind trial compared the use of a standardized extract of St. John’s wort (Hypericum perforatum) to a placebo for treating major depression of...
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ورودعنوان ژورنال:
- Evidence-based mental health
دوره 5 4 شماره
صفحات -
تاریخ انتشار 2002